Characterization of the antiproliferative signal mediated by the somatostatin receptor subtype sst5

Eitemau Tebyg

• Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238
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  Cyhoeddwyd: (2000)
• Induction of a negative autocrine loop by expression of sst2 somatostatin receptor in NIH 3T3 cells.
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• Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis
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  Cyhoeddwyd: (2003)
• Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms.
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  Cyhoeddwyd: (1995)
• Critical Role of Src and SHP-2 in sst2 Somatostatin Receptor-mediated Activation of SHP-1 and Inhibition of Cell Proliferation
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  Cyhoeddwyd: (2003)