p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression.
Cyclin E is necessary and rate limiting for the passage of mammalian cells through the G1 phase of the cell cycle. Control of cell cycle progression by cyclin E involves cdk2 kinase, which requires cyclin E for catalytic activity. Expression of cyclin E/cdk2 leads to an activation of cyclin A gene e...
Zapisane w:
| Wydane w: | Mol Cell Biol |
|---|---|
| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1997
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972221/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.407 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
