Adenovirus E1A activates cyclin A gene transcription in the absence of growth factors through interaction with p107.

Using the infection of quiescent human fibroblasts with adenovirus type 5 and various deletion mutants, we show that E1A can stimulate transcription of the cyclin A gene in the absence of exogenous growth factors. Required for this activity is conserved region 2 (CR2), while both the N-terminal part...

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Bibliografiske detaljer
Main Authors: Zerfass, K, Spitkovsky, D, Schulze, A, Joswig, S, Henglein, B, Jansen-Dürr, P
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC190115/
https://ncbi.nlm.nih.gov/pubmed/8642699
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