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Adenovirus E1A activates cyclin A gene transcription in the absence of growth factors through interaction with p107.

Using the infection of quiescent human fibroblasts with adenovirus type 5 and various deletion mutants, we show that E1A can stimulate transcription of the cyclin A gene in the absence of exogenous growth factors. Required for this activity is conserved region 2 (CR2), while both the N-terminal part...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Zerfass, K, Spitkovsky, D, Schulze, A, Joswig, S, Henglein, B, Jansen-Dürr, P
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1996
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190115/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642699/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2637-2642.1996
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