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Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor.

The initiation of DNA replication in Saccharomyces cerevisiae requires the action of a multisubunit complex of six proteins known as the origin recognition complex (ORC). The identification of higher eukaryotic homologs of several ORC components suggests a universal role for this complex in DNA repl...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphov: Ohtani, K, DeGregori, J, Leone, G, Herendeen, D R, Kelly, T J, Nevins, J R
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231701/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6977
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