Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor.

The initiation of DNA replication in Saccharomyces cerevisiae requires the action of a multisubunit complex of six proteins known as the origin recognition complex (ORC). The identification of higher eukaryotic homologs of several ORC components suggests a universal role for this complex in DNA repl...

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Publicado en:	Mol Cell Biol
Autores principales:	Ohtani, K, DeGregori, J, Leone, G, Herendeen, D R, Kelly, T J, Nevins, J R
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6977
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