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E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

Various experiments have demonstrated a role for the E2F transcription factor in the regulation of cell growth during the G0/G1/S phase transition. Indeed, overexpression of the E2F1 product, a component of the cellular E2F activity, induces DNA synthesis in quiescent fibroblasts. To provide an appr...

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Detalhes bibliográficos
Main Authors: Kowalik, T F, DeGregori, J, Schwarz, J K, Nevins, J R
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188925/
https://ncbi.nlm.nih.gov/pubmed/7884898
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