E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.
Various experiments have demonstrated a role for the E2F transcription factor in the regulation of cell growth during the G0/G1/S phase transition. Indeed, overexpression of the E2F1 product, a component of the cellular E2F activity, induces DNA synthesis in quiescent fibroblasts. To provide an appr...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2491-2500.1995 |
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