A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1.
The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms' tumor. In this study, we identified par-4 (for prostate apoptosis response) as a WT1-interacting protein that itself functions as a transcrip...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6945 |
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