Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.
Wilms tumor, an embryonic kidney malignancy, accounts for approximately 6% of all pediatric neoplasms. A gene implicated in the genesis of this tumor, the Wilms tumor suppressor gene (WT1), encodes a zinc-finger DNA-binding protein (WT1) that functions as a transcriptional repressor. In certain Wilm...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1332065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10984 |
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