A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens

Experimental autoimmune encephalomyelitis (EAE) induced with myelin proteolipid protein (PLP) residues 139–151 (HSLGKWLGHPDKF) can be prevented by treatment with a T cell receptor (TCR) antagonist peptide (L144/R147) generated by substituting at the two principal TCR contact residues in the encephal...

Full description

Saved in:
Bibliographic Details
Main Authors: Nicholson, Lindsay B., Murtaza, Anwar, Hafler, Brian P., Sette, Alessandro, Kuchroo, Vijay K.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC23155/
https://ncbi.nlm.nih.gov/pubmed/9256473
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items