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Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1

This study addresses the issue of the effect of immunomodulating therapies in the target organ—the central nervous system (CNS)—in the case of multiple sclerosis. Copolymer 1 (Cop 1, Copaxone, glatiramer acetate), an approved drug for the treatment of multiple sclerosis, is a potent inducer of Th2 r...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Aharoni, Rina, Teitelbaum, Dvora, Leitner, Orith, Meshorer, Asher, Sela, Michael, Arnon, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11472
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