A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens

Experimental autoimmune encephalomyelitis (EAE) induced with myelin proteolipid protein (PLP) residues 139–151 (HSLGKWLGHPDKF) can be prevented by treatment with a T cell receptor (TCR) antagonist peptide (L144/R147) generated by substituting at the two principal TCR contact residues in the encephal...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Nicholson, Lindsay B., Murtaza, Anwar, Hafler, Brian P., Sette, Alessandro, Kuchroo, Vijay K.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9256473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.17.9279
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