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Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function.

The p53 tumor suppressor protein is a sequence-specific transcriptional activator, a function which contributes to cell cycle arrest and apoptosis induced by p53 in appropriate cell types. Analysis of a series of p53 point mutants has revealed the potential for selective loss of the ability to trans...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ludwig, R L, Bates, S, Vousden, K H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC231497/
https://ncbi.nlm.nih.gov/pubmed/8756654
Tagiau: Ychwanegu Tag
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