Anchorage-dependent transcription of the cyclin A gene.

NIH 3T3 cells cultured in suspension fail to express cyclin A and hence cannot enter S phase and divide. We show that loss of cell adhesion to substratum abrogates cyclin A gene expression by blocking its promoter activity through the E2F site that mediates its cell cycle regulation in adherent cell...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Schulze, A, Zerfass-Thome, K, Bergès, J, Middendorp, S, Jansen-Dürr, P, Henglein, B
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.4632
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