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Anchorage-dependent transcription of the cyclin A gene.

NIH 3T3 cells cultured in suspension fail to express cyclin A and hence cannot enter S phase and divide. We show that loss of cell adhesion to substratum abrogates cyclin A gene expression by blocking its promoter activity through the E2F site that mediates its cell cycle regulation in adherent cell...

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Detalhes bibliográficos
Main Authors: Schulze, A, Zerfass-Thome, K, Bergès, J, Middendorp, S, Jansen-Dürr, P, Henglein, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231462/
https://ncbi.nlm.nih.gov/pubmed/8756619
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