Anchorage-dependent transcription of the cyclin A gene.
NIH 3T3 cells cultured in suspension fail to express cyclin A and hence cannot enter S phase and divide. We show that loss of cell adhesion to substratum abrogates cyclin A gene expression by blocking its promoter activity through the E2F site that mediates its cell cycle regulation in adherent cell...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.4632 |
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