Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA.

We have analyzed Chinese hamster ovary (CHO) cell mutants bearing nonsense codons in four of the five exons of the adenine phosphoribosyltransferase (aprt) gene and have found a pattern of mRNA reduction similar to that seen in systems studied previously: a decrease in steady-state mRNA levels of 5-...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Kessler, O, Chasin, L A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4426
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