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Analysis and in vitro localization of internal methylated adenine residues in dihydrofolate reductase mRNA.

A T7 RNA transcript coding for mouse dihydrofolate reductase (DHFR) was utilized as a substrate for the N6-methyladenosine mRNA methyltransferase isolated from HeLa cell nuclei. This transcript acted as a 3 fold better substrate than either prolactin mRNA or a synthetic RNA substrate which contained...

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Detalhes bibliográficos
Main Authors: Rana, A P, Tuck, M T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC331949/
https://ncbi.nlm.nih.gov/pubmed/2395644
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