Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.

Phosphatidylinositol (PI) 3-kinase is a cytoplasmic signaling molecule recruited to the membrane by activated growth factor receptors. The p85 subunit of PI 3-kinase links the catalytic p110 subunit to activated growth factor receptors and is required for enzymatic activity of p110. In this report,...

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Bibliografiske detaljer
Main Authors: Klippel, A, Reinhard, C, Kavanaugh, W M, Apell, G, Escobedo, M A, Williams, L T
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC231408/
https://ncbi.nlm.nih.gov/pubmed/8754810
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