Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.

Phosphatidylinositol (PI) 3-kinase is a cytoplasmic signaling molecule recruited to the membrane by activated growth factor receptors. The p85 subunit of PI 3-kinase links the catalytic p110 subunit to activated growth factor receptors and is required for enzymatic activity of p110. In this report,...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Klippel, A, Reinhard, C, Kavanaugh, W M, Apell, G, Escobedo, M A, Williams, L T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4117
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