Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

To examine the function of murine beta-globin locus region (LCR) 5' hypersensitive site 3 (HS3) in its native chromosomal context, we deleted this site from the mouse germ line by using homologous recombination techniques. Previous experiments with human 5' HS3 in transgenic models suggest...

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Main Authors: Hug, B A, Wesselschmidt, R L, Fiering, S, Bender, M A, Epner, E, Groudine, M, Ley, T J
格式: Artigo
語言:Inglês
出版: 1996
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC231284/
https://ncbi.nlm.nih.gov/pubmed/8649401
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