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Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

To examine the function of murine beta-globin locus region (LCR) 5' hypersensitive site 3 (HS3) in its native chromosomal context, we deleted this site from the mouse germ line by using homologous recombination techniques. Previous experiments with human 5' HS3 in transgenic models suggested that th...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Hug, B A, Wesselschmidt, R L, Fiering, S, Bender, M A, Epner, E, Groudine, M, Ley, T J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231284/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.2906
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