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Low free energy cost of very long loop insertions in proteins

Long insertions into a loop of a folded host protein are expected to have destabilizing effects because of the entropic cost associated with loop closure unless the inserted sequence adopts a folded structure with amino- and carboxy-termini in close proximity. A loop entropy reduction screen based o...

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Bibliografiset tiedot
Päätekijät: Scalley-Kim, Michelle, Minard, Philippe, Baker, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312413/
https://ncbi.nlm.nih.gov/pubmed/12538883
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