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Free-energy cost for translocon-assisted insertion of membrane proteins

Nascent membrane proteins typically insert in a sequential fashion into the membrane via a protein-conducting channel, the Sec translocon. How this process occurs is still unclear, although a thermodynamic partitioning between the channel and the membrane environment has been proposed. Experiment- a...

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Detalhes bibliográficos
Main Authors: Gumbart, James, Chipot, Christophe, Schulten, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048118/
https://ncbi.nlm.nih.gov/pubmed/21317362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012758108
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