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Determination of Membrane-Insertion Free Energies by Molecular Dynamics Simulations

The accurate prediction of membrane-insertion probability for arbitrary protein sequences is a critical challenge to identifying membrane proteins and determining their folded structures. Although algorithms based on sequence statistics have had moderate success, a complete understanding of the ener...

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Detaylı Bibliyografya
Asıl Yazarlar: Gumbart, James, Roux, Benoît
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283816/
https://ncbi.nlm.nih.gov/pubmed/22385850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.021
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