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On the energetics of translocon-assisted insertion of charged transmembrane helices into membranes

The understanding of the mechanism of insertion of transmembrane (TM) helixes through the translocon presents a major open challenge. Although the experimental information about the partition of the inserted helices between the membrane and the solution contains crucial information about this proces...

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Detalhes bibliográficos
Main Authors: Rychkova, Anna, Vicatos, Spyridon, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955132/
https://ncbi.nlm.nih.gov/pubmed/20876127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012207107
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