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Stably folded de novo proteins from a designed combinatorial library

Binary patterning of polar and nonpolar amino acids has been used as the key design feature for constructing large combinatorial libraries of de novo proteins. Each position in a binary patterned sequence is designed explicitly to be either polar or nonpolar; however, the precise identities of these...

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Библиографические подробности
Главные авторы: Wei, Yinan, Liu, Tun, Sazinsky, Stephen L., Moffet, David A., Pelczer, István, Hecht, Michael H.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312408/
https://ncbi.nlm.nih.gov/pubmed/12493832
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