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Stably folded de novo proteins from a designed combinatorial library

Binary patterning of polar and nonpolar amino acids has been used as the key design feature for constructing large combinatorial libraries of de novo proteins. Each position in a binary patterned sequence is designed explicitly to be either polar or nonpolar; however, the precise identities of these...

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Auteurs principaux: Wei, Yinan, Liu, Tun, Sazinsky, Stephen L., Moffet, David A., Pelczer, István, Hecht, Michael H.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312408/
https://ncbi.nlm.nih.gov/pubmed/12493832
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