Binding of small molecules to cavity forming mutants of a de novo designed protein

A central goal of protein design is to devise novel proteins for applications in biotechnology and medicine. Many applications, including those focused on sensing and catalysis will require proteins that recognize and bind to small molecules. Here, we show that stably folded α-helical proteins isola...

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Bibliographic Details
Main Authors: Das, Aditi, Wei, Yinan, Pelczer, Istvan, Hecht, Michael H
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081548/
https://ncbi.nlm.nih.gov/pubmed/21328630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.601
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