Spi-1/PU.1 transgenic mice develop multistep erythroleukemias.
Insertional mutagenesis of the spi-1 gene is associated with the emergence of malignant proerythroblasts during Friend virus-induced acute erythroleukemia. To determine the role of spi-1/PU.1 in the genesis of leukemia, we generated spi-1 transgenic mice. In one founder line the transgene was overex...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231234/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628313/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2453 |
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