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The Spi-1/PU.1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-J kappa interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element.

Epstein-Barr virus (EBV) immortalizes resting human B cells very efficiently in vitro. The EBV nuclear protein EBNA2 is absolutely required for this process. It also activates transcription of cellular, as well as viral, genes. It is assumed that EBNA2 contributes to B cell immortalization by its tr...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Laux, G, Adam, B, Strobl, L J, Moreau-Gachelin, F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7988559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06900.x
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