The Spi-1/PU.1 and Spi-B ets family transcription factors and the recombination signal binding protein RBP-J kappa interact with an Epstein-Barr virus nuclear antigen 2 responsive cis-element.

Epstein-Barr virus (EBV) immortalizes resting human B cells very efficiently in vitro. The EBV nuclear protein EBNA2 is absolutely required for this process. It also activates transcription of cellular, as well as viral, genes. It is assumed that EBNA2 contributes to B cell immortalization by its tr...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Laux, G, Adam, B, Strobl, L J, Moreau-Gachelin, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395527/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7988559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06900.x
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