Functional Replacement of the Intracellular Region of the Notch1 Receptor by Epstein-Barr Virus Nuclear Antigen 2

The intracellular region (RAMIC) of the mouse Notch1 receptor interacts with RBP-J/CBF-1, which binds to the DNA sequence CGTGGGAA and suppresses differentiation by transcriptional activation of genes regulated by RBP-J. Epstein-Barr virus nuclear antigen 2 (EBNA2) is essential for immortalization o...

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Detalhes bibliográficos
Main Authors: Sakai, Takashi, Taniguchi, Yoshihito, Tamura, Kumiko, Minoguchi, Shigeru, Fukuhara, Takataro, Strobl, Lothar J., Zimber-Strobl, Ursula, Bornkamm, George W., Honjo, Tasuku
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110408/
https://ncbi.nlm.nih.gov/pubmed/9621066
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