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Spi-1/PU.1 transgenic mice develop multistep erythroleukemias.

Insertional mutagenesis of the spi-1 gene is associated with the emergence of malignant proerythroblasts during Friend virus-induced acute erythroleukemia. To determine the role of spi-1/PU.1 in the genesis of leukemia, we generated spi-1 transgenic mice. In one founder line the transgene was overex...

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Publicado no:Mol Cell Biol
Principais autores: Moreau-Gachelin, F, Wendling, F, Molina, T, Denis, N, Titeux, M, Grimber, G, Briand, P, Vainchenker, W, Tavitian, A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628313/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2453
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