MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)

The recurring translocation t(11;16)(q23;p13.3) has been documented only in cases of acute leukemia or myelodysplasia secondary to therapy with drugs targeting DNA topoisomerase II. We show that the MLL gene is fused to the gene that codes for CBP (CREB-binding protein), the protein that binds speci...

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Autors principals: Sobulo, Olatoyosi M., Borrow, Julian, Tomek, Ronald, Reshmi, Shalini, Harden, Alanna, Schlegelberger, Brigitte, Housman, David, Doggett, Norman A., Rowley, Janet D., Zeleznik-Le, Nancy J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23102/
https://ncbi.nlm.nih.gov/pubmed/9238046
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