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p16INK4a Gene Promoter Hypermethylation in Mucosa as a Prognostic Factor for Patients with Colorectal Cancer

Low gene expression of folylpolyglutamate synthase (FPGS) in colorectal mucosa correlates with low folate levels and poor survival of colorectal cancer (CRC) patients. Because gene-specific hypermethylation is affected by the folate level, the hypermethylation status in mucosa may also be linked to...

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Detalhes bibliográficos
Main Authors: Wettergren, Yvonne, Odin, Elisabeth, Nilsson, Staffan, Carlsson, Göran, Gustavsson, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2309648/
https://ncbi.nlm.nih.gov/pubmed/18418463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00096.Wettergren
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