E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis.

The E2F DNA binding activity consists of a heterodimer between E2F and DP family proteins, and these interactions are required for association of E2F proteins with pRb and the pRb-related proteins p107 and p130, which modulate E2F transcriptional activities. E2F-1 expression is sufficient to release...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Hiebert, S W, Packham, G, Strom, D K, Haffner, R, Oren, M, Zambetti, G, Cleveland, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.6864
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!