E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis.
The E2F DNA binding activity consists of a heterodimer between E2F and DP family proteins, and these interactions are required for association of E2F proteins with pRb and the pRb-related proteins p107 and p130, which modulate E2F transcriptional activities. E2F-1 expression is sufficient to release...
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| Publicado en: | Mol Cell Biol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
1995
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.6864 |
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