Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor.

DNA topoisomerase II (topo II) is an essential nuclear enzyme involved in major cellular functions such as DNA replication, transcription, recombination, and mitosis. While an elevated level of topo II alpha is associated with cell proliferation, wild-type (wt) p53 inhibits the expression of various...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Wang, Q, Zambetti, G P, Suttle, D P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972219/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.1.389
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