In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

We have developed a technique, methylation-specific PCR in situ hybridization (MSP-ISH), which allows for the methylation status of specific DNA sequences to be visualized in individual cells. We use MSP-ISH to monitor the timing and consequences of aberrant hypermethylation of the p16 tumor suppres...

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Detaylı Bibliyografya
Asıl Yazarlar: Nuovo, Gerard J., Plaia, Todd W., Belinsky, Steven A., Baylin, Stephen B., Herman, James G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC23084/
https://ncbi.nlm.nih.gov/pubmed/10535995
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