Early Detection of Lung Cancer using DNA Promoter Hypermethylation in Plasma and Sputum

PURPOSE: CT screening can reduce death from lung cancer. We sought to improve the diagnostic accuracy of lung cancer screening using ultrasensitive methods and a lung cancer specific gene panel to detect DNA methylation in sputum and Plasma. EXPERIMENTAL DESIGN: This is a case-control study of subje...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Principais autores: Hulbert, Alicia, Jusue-Torres, Ignacio, Stark, Alejandro, Chen, Chen, Rodgers, Kristen, Lee, Beverly, Griffin, Candace, Yang, Andrew, Huang, Peng, Wrangle, John, Belinsky, Steven A, Wang, Tza-Huei, Yang, Stephen C, Baylin, Stephen B, Brock, Malcolm V, Herman, James G
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366618/
https://ncbi.nlm.nih.gov/pubmed/27729459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1371
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