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DREAMing: a simple and ultrasensitive method for assessing intratumor epigenetic heterogeneity directly from liquid biopsies

Many cancers comprise heterogeneous populations of cells at primary and metastatic sites throughout the body. The presence or emergence of distinct subclones with drug-resistant genetic and epigenetic phenotypes within these populations can greatly complicate therapeutic intervention. Liquid biopsie...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pisanic, Thomas R., Athamanolap, Pornpat, Poh, Weijie, Chen, Chen, Hulbert, Alicia, Brock, Malcolm V., Herman, James G., Wang, Tza-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678844/
https://ncbi.nlm.nih.gov/pubmed/26304549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv795
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