DREAMing: a simple and ultrasensitive method for assessing intratumor epigenetic heterogeneity directly from liquid biopsies

Many cancers comprise heterogeneous populations of cells at primary and metastatic sites throughout the body. The presence or emergence of distinct subclones with drug-resistant genetic and epigenetic phenotypes within these populations can greatly complicate therapeutic intervention. Liquid biopsie...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Pisanic, Thomas R., Athamanolap, Pornpat, Poh, Weijie, Chen, Chen, Hulbert, Alicia, Brock, Malcolm V., Herman, James G., Wang, Tza-Huei
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678844/
https://ncbi.nlm.nih.gov/pubmed/26304549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv795
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