Single-tube Analysis of DNA Methylation Using Silica Superparamagnetic Beads

BACKGROUND: DNA promoter methylation is a signature for silencing of tumor suppressor genes. Most widely used methods to detect DNA methylation involve three separate independent processes that include DNA extraction, bisulfite conversion and methylation detection through PCR, such as methylation sp...

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Main Authors: Bailey, Vasudev J., Zhang, Yi, Keeley, Brian P., Yin, Chao, Pelosky, Kristen L., Brock, Malcolm, Baylin, Stephen B., Herman, James G., Wang, Tza-Huei
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000409/
https://ncbi.nlm.nih.gov/pubmed/20360128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2009.140244
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