Extraction and Processing of Circulating DNA from Large Sample Volumes using Methylation on Beads for the Detection of Rare Epigenetic Events

The use of methylated tumor-specific circulating DNA has shown great promise as a potential cancer biomarker. Nonetheless, the relative scarcity of tumor-specific circulating DNA presents a challenge for traditional DNA extraction and processing techniques. Here we demonstrate a single tube extracti...

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Detalhes bibliográficos
Main Authors: Keeley, Brian, Stark, Alejandro, Pisanic, Thomas R., Kwak, Ruby, Zhang, Yi, Wrangle, John, Baylin, Stephen, Herman, James, Ahuja, Nita, Wang, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963364/
https://ncbi.nlm.nih.gov/pubmed/23911908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2013.07.023
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