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Single-tube Analysis of DNA Methylation Using Silica Superparamagnetic Beads

BACKGROUND: DNA promoter methylation is a signature for silencing of tumor suppressor genes. Most widely used methods to detect DNA methylation involve three separate independent processes that include DNA extraction, bisulfite conversion and methylation detection through PCR, such as methylation sp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bailey, Vasudev J., Zhang, Yi, Keeley, Brian P., Yin, Chao, Pelosky, Kristen L., Brock, Malcolm, Baylin, Stephen B., Herman, James G., Wang, Tza-Huei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000409/
https://ncbi.nlm.nih.gov/pubmed/20360128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2009.140244
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