E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis.

In breast cancer, inactivating point mutations in the E-cadherin gene are frequently found in invasive lobular carcinoma (ILC) but never in invasive ductal carcinoma (IDC). Lobular carcinoma in situ (LCIS) adjacent to ILC has previously been shown to lack E-cadherin expression, but whether LCIS with...

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Hlavní autoři: Vos, C. B., Cleton-Jansen, A. M., Berx, G., de Leeuw, W. J., ter Haar, N. T., van Roy, F., Cornelisse, C. J., Peterse, J. L., van de Vijver, M. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1997
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228132/
https://ncbi.nlm.nih.gov/pubmed/9365159
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