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E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer?

Loss of heterozygosity at the long arm of chromosome 16 is one of the most frequent genetic events in breast cancer. In the search for tumour suppressor genes that are the target of loss of heterozygosity at 16q, the E-cadherin gene CDH1 was unveiled by the identification of truncating mutations in...

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Bibliografiske detaljer
Hovedforfatter: Cleton-Jansen, Anne-Marie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC138715/
https://ncbi.nlm.nih.gov/pubmed/11879552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr416
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