E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis.

In breast cancer, inactivating point mutations in the E-cadherin gene are frequently found in invasive lobular carcinoma (ILC) but never in invasive ductal carcinoma (IDC). Lobular carcinoma in situ (LCIS) adjacent to ILC has previously been shown to lack E-cadherin expression, but whether LCIS with...

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Main Authors: Vos, C. B., Cleton-Jansen, A. M., Berx, G., de Leeuw, W. J., ter Haar, N. T., van Roy, F., Cornelisse, C. J., Peterse, J. L., van de Vijver, M. J.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1997
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228132/
https://ncbi.nlm.nih.gov/pubmed/9365159
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