Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis.

BCR-ABL is a deregulated tyrosine kinase expressed in Philadelphia chromosome-positive human leukemias. Prolongation of hematopoietic cell survival by inhibition of apoptosis has been proposed to be an integral component of BCR-ABL-induced chronic myelogenous leukemia. BCR-ABL elicits transformation...

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Publicado en:	Mol Cell Biol
Autores principales:	Cortez, D, Kadlec, L, Pendergast, A M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.10.5531
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